The first lady and I watched the first couple episodes of Lost and quickly lost interest. But since the great Brett loves it so much, maybe we'll try again, out of respect. Still have to watch Weeds (again) and Californication (again) to get (re)caught up on the new episodes. Just finished Breaking Bad (GREAT SHOW!).
Also, since I'm in a drunken-rambling sort of mood. If you haven't watched these shows, you need to take a step back and re-evaluate the choices you're making in your life.
The Wire (Favorite show ever)
Game of Thrones
Sons of Anarchy
Nip-Tuck (Guilty pleasure)
Six Feet Under
Eastbound & Down (Funniest show ever)
Hell on Wheels
News-FUCKING-radio (Greatest sitcom ever)
Prison Break (I was high last year, so it might not have been that good)
Rick - our shows overlap A TON. For that reason, I'd be really surprised if you didn't like 'LOST.'
Also, for those who like 'The Walking Dead,' that is - to me - the show most evocative of 'LOST' since it went off the air.