Thursday Night Football takes us out west to kick off week 6 of the NFL season as the 49ers take on the Seahawks. The 49ers are a slight favorite in the game. Let’s check out the odds and matchup for Thursday night at 8:15 pm ET on Amazon Prime.
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49ers at Seahawks Odds
The 49ers (2-3) enter the game looking to even their record at 3-3 and catch the Seahawks (3-2) who sit on top of the NFC West. Check out the odds for the game which you can catch on Amazon Prime on Thursday at 8:15 pm ET.
Thurs. 8:15 pm ET | Spread | Total | ML |
---|---|---|---|
49ers | -3.5 (-102) | O 49 (-110) | -170 |
Seahawks | +3.5 (-118) | U 49 (-110) | +142 |
49ers Have Lost 3 of 4

The 49ers looked great in week 1 of the season as they dismantled the Jets 32-19 without Christian McCaffrey. Jordan Mason has been stellar in replacing McCaffrey but the 49ers still haven’t been able to find their footing in 2024. They have lost 3 of their last 4 games as they were beaten by the Vikings, Rams, and Cardinals.
Jordan Mason has run for 536 yards and 3 touchdowns while Brock Purdy has thrown for 1,374 yards with 6 touchdowns and 4 interceptions. The 49ers need to get moving quickly because their schedule is not doing them any favors. Matchups with the Chiefs, Cowboys, Bucs, Packers, and Bills are still ahead.
Seahawks Have Dropped 2 Straight
The Seahawks started 3-0 and were looking like they were a legitimate threat in the NFC but the team is now scrambling after back-to-back losses. First, it was a 42-29 loss on Monday Night Football to the Lions before getting beat by the Giants 29-20 last week.
Geno Smith has been slinging it all over the field as he leads the NFL in passing yards with 1,466 but it hasn’t been enough to pick up wins in the past two weeks. The run game is in the bottom third of the NFL and averages just 105.4 yards per game. Kenneth Walker leads the team with 204 yards and 4 rushing TDs but he had just 19 rushing yards in the loss to the Giants.
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