Giants vs. Cardinals Prediction: Expert Picks, Odds, Stats & Best Bets – Wednesday, April 26, 2023

The San Francisco Giants (10-13) host the St. Louis Cardinals (9-15) on Wednesday at 9:45 PM ET(broadcast on NBCS-BA+). Sportsbooks have opted not to choose a favorite on the moneyline for the contest, installing pick ’em odds, instead.

Anthony DeSclafani will get the ball for San Francisco while St. Louis will counter with Steven Matz.

Giants vs. Cardinals Odds

  • Giants odds to win: -110
  • Cardinals odds to win: -110
  • Spread: Cardinals -1.5
  • Total: 8.5 runs
  • Giants vs. Cardinals Promo Codes

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    Game Time and Information

  • Date: Wednesday, April 26, 2023
  • Time: 9:45 PM ET
  • TV: NBCS-BA+
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    Who Will Win Giants vs. Cardinals?

    Giants and Cardinals Betting Trends

    The Giants have compiled a 4-5 record in games they were favored on the moneyline (winning 44.4% of those games).

    When playing as moneyline favorites with odds of -110 or shorter, San Francisco has a record of 4-5 (44.4%).

    The Cardinals have won one of the nine games they’ve played as underdogs this season.

    St. Louis is 1-8 this season when entering a game as the underdog by -110 or more on the moneyline.

    The Giants have had an over/under set by oddsmakers 23 times, and have combined with opponents to go over the total in 11 of those games (11-11-1).

    Games involving the Cardinals have gone over the total set by sportsbooks in 10 of 24 chances this season.

    Giants Stats & Insights

    The Giants have the No. 19 offense in MLB action scoring 4.5 runs per game (104 total runs).

    San Francisco is fourth-best in baseball with 36 total home runs.

    The Giants have the 19th-ranked batting average in the majors (.237).

    San Francisco strikes out 10.7 times per game, the worst mark in the majors.

    The Giants pitching staff ranks 13th in the majors with a collective 9.2 strikeouts per nine innings.

    San Francisco has a 4.45 team ERA that ranks 18th across all MLB pitching staffs.

    Cardinals Stats & Insights

    The Cardinals have scored the 16th-most runs in the league this season with 108 (4.5 per game).

    St. Louis has hit 28 homers this season, which ranks 13th in the majors.

    The Cardinals rank fourth in MLB with a .266 team batting average.

    St. Louis is one of the best teams in baseball at making contact this season, ranking eighth with an average of 8.2 strikeouts per game.

    The Cardinals have a 9.3 K/9 this season as a pitching staff, eighth-best in baseball.

    St. Louis has pitched to a 4.39 ERA this season, which ranks 17th in baseball.

    Giants Key Players to Watch

    DeSclafani (1-1) gets the starting nod for the Giants in his fifth start of the season. He has a 2.63 ERA in 24 2/3 innings pitched, with 21 strikeouts.

    Thairo Estrada leads San Francisco in batting average (.310) this season while adding four home runs and seven RBI.

    Mike Yastrzemski leads San Francisco in home runs with five while driving in 13 runs and slugging .535.

    J.D. Davis leads the club in homers (five) and runs batted in (16) this season.

    Wilmer Flores has 19 hits and an OBP of .324 to go with a slugging percentage of .463 this season.

    Cardinals Key Players to Watch

    The Cardinals will send Matz (0-3) to the mound for his fifth start this season.

    Nolan Gorman has put up a team-best batting average of .293, and leads the Cardinals in home runs (six) and runs batted in (22).

    Paul Goldschmidt is batting .287 with seven doubles, two home runs and 15 walks.

    Tommy Edman is hitting .267 with two doubles, a triple, four home runs and 11 walks.

    Willson Contreras has six doubles, two home runs and 10 walks while batting .260.

    Giants and Cardinals Injuries

    Giants: Darin Ruf: 10 Day IL (Wrist), Austin Slater: 10 Day IL (Elbow), Mitch Haniger: 10 Day IL (Oblique), Alex Wood: 15 Day IL (Hamstring), Roberto Pérez: 60 Day IL (Shoulder), Luke Jackson: 60 Day IL (Elbow), Luis González: 60 Day IL (Back), Thomas Szapucki: 60 Day IL (Left arm), Bryce Johnson: 7 Day IL (Concussion)

    Cardinals: Packy Naughton: 15 Day IL (Forearm), Adam Wainwright: 15 Day IL (Groin), Wilking Rodriguez: 15 Day IL (Shoulder)

    Giants vs. Cardinals Prediction

  • Score Prediction: Giants 7, Cardinals 6
  • Total Prediction: Over 8.5 runs
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    How to Bet on Giants vs. Cardinals

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    written by

    Matt is from the Chicagoland area and has been working in Chicago sports since 2015 with stops at WGN Radio, the Chicago Blackhawks, Stadium, and NBC Sports Chicago prior to landing at Betsperts. Matt covers just about everything for Betsperts and Bleacher Nation but focuses on the NHL and college football.

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