White Sox vs. Guardians Prediction: Expert Picks, Odds, Stats & Best Bets – Thursday, May 18, 2023

The Chicago White Sox (16-28), led by Jake Burger on a three-game home run streak, are -146 favorites on the moneyline to defeat the Cleveland Guardians (19-23). First pitch is set for 2:10 PM ET Thursday, live from Guaranteed Rate Field and airing on NBCS-CHI.

Dylan Cease will get the ball for Chicago while Cleveland will counter with Logan Allen.

White Sox vs. Guardians Odds

  • White Sox odds to win: -146
  • Guardians odds to win: +125
  • Spread: White Sox -1.5
  • Total: 7.5 runs
  • White Sox vs. Guardians Promo Codes

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    Game Time and Information

  • Date: Thursday, May 18, 2023
  • Time: 2:10 PM ET
  • TV: NBCS-CHI
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    Who Will Win White Sox vs. Guardians?

    White Sox and Guardians Betting Trends

    The White Sox have been the moneyline favorite 13 total times this season. They’ve finished 7-6 in those games.

    Chicago has played as moneyline favorites of -146 or shorter in just one game this season, which it lost.

    The Guardians have been underdogs in 15 games this season and won seven (46.7%) of those contests.

    Cleveland has a record of 2-2 when it’s set as an underdog of +125 or more by sportsbooks this season.

    In the 43 games in which oddsmakers have set an over/under for the White Sox, they have combined with opponents to go over the total 23 times (23-17-3).

    Games involving the Guardians have gone over the total set by oddsmakers in 16 of 41 chances this season.

    White Sox Stats & Insights

    The White Sox have the No. 17 offense in MLB action scoring 4.3 runs per game (190 total runs).

    Chicago averages 1.1 home runs per game to rank 15th in MLB action with 50 total home runs .

    The White Sox’s .244 batting average ranks 16th in MLB.

    Chicago’s 8.4 strikeouts per game rank 12th in MLB.

    The White Sox pitching staff is third in the majors with a collective 9.7 strikeouts per nine innings.

    Chicago has a 5.32 team ERA that ranks 29th among all MLB pitching staffs.

    Guardians Stats & Insights

    The Guardians have scored 147 runs (just 3.5 per game) this season, which ranks 29th in MLB.

    Cleveland ranks last in Major League Baseball with just 23 home runs as a team.

    The Guardians have a team batting average of just .227 this season, which ranks 28th among MLB teams.

    Cleveland is one of the best teams in baseball at making contact this season, ranking second with an average of 7.5 strikeouts per game.

    The Guardians have a 7.5 K/9 this season as a pitching staff, which ranks 29th in baseball.

    Cleveland has the ninth-best ERA (3.88) in the majors this season.

    White Sox Key Players to Watch

    Cease (2-2) gets the starting nod for the White Sox in his 10th start of the season. He’s put together a 4.86 ERA in 46 1/3 innings pitched, with 54 strikeouts.

    Luis Robert leads Chicago in home runs this season with 12 while driving in 28 runs.

    Andrew Vaughn leads Chicago in runs batted in with 31 while batting .242 with five homers.

    Andrew Benintendi is slashing .277/.337/.348 this season for the White Sox.

    Burger has 22 hits and an OBP of .348 to go with a slugging percentage of .747 this season.

    Guardians Key Players to Watch

    Allen (1-1) will take the mound for the Guardians, his fifth start of the season.

    Steven Kwan has nine doubles, a triple, a home run and 24 walks while batting .276.

    Josh Naylor has put his power on display as he paces his team with six home runs and 26 runs batted in.

    Josh Bell is batting .226 with 10 doubles, three home runs and 26 walks.

    Andres Gimenez is batting .231 with seven doubles, a triple, three home runs and eight walks.

    White Sox and Guardians Injuries

    White Sox: Elvis Andrus: 10 Day IL (Oblique), Billy Hamilton: 10 Day IL (Hamstring), Eloy Jiménez: 10 Day IL (Appendix), Liam Hendriks: 15 Day IL (Illness), Matt Foster: 60 Day IL (Forearm)

    Guardians: Aaron Civale: 15 Day IL (Oblique), Triston McKenzie: 60 Day IL (Shoulder), Cody Morris: 60 Day IL (Shoulder), Josh Naylor: day-to-day (Leg)

    White Sox vs. Guardians Prediction

  • Score Prediction: White Sox 6, Guardians 5
  • Total Prediction: Over 7.5 runs
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    How to Bet on White Sox vs. Guardians

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    written by

    Matt is from the Chicagoland area and has been working in Chicago sports since 2015 with stops at WGN Radio, the Chicago Blackhawks, Stadium, and NBC Sports Chicago prior to landing at Betsperts. Matt covers just about everything for Betsperts and Bleacher Nation but focuses on the NHL and college football.

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