Orioles vs. Cardinals Prediction: Expert Picks, Odds, Stats & Best Bets – Wednesday, May 22, 2024

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The Baltimore Orioles (29-16), led by the red-hot Gunnar Henderson and his four-game homer streak, are -126 favorites to pick up a win over the St. Louis Cardinals (21-26) Wednesday at 1:15 PM ET, live from Busch Stadium and broadcast on MASN2.

Baltimore’s John Means and St. Louis’ Kyle Gibson have been named the starters for this contest.

Orioles vs. Cardinals Odds

  • Orioles odds to win: -126
  • Cardinals odds to win: +107
  • Spread: Orioles -1.5
  • Total: 9 runs
  • Orioles vs. Cardinals Promo Codes

    Game Time and Information

  • Date: Wednesday, May 22, 2024
  • Time: 1:15 PM ET
  • TV: MASN2
  • Who Will Win Orioles vs. Cardinals?

    Orioles and Cardinals Betting Trends

    The Orioles have been favored on the moneyline 36 total times this season. They’ve finished 22-14 in those games.

    Baltimore has gone 18-13 (winning 58.1% of its games) when it has played as moneyline favorites of -126 or shorter.

    The Cardinals have been underdogs in 22 games this season and won nine (40.9%) of those contests.

    St. Louis has a record of 5-9, a 35.7% win rate, when it’s set as an underdog of +107 or more by sportsbooks this season.

    The Orioles have had an over/under set by oddsmakers 45 times, and have combined with opponents to go over the total in 23 of those games (23-18-4).

    Games involving the Cardinals have gone over the total set by bookmakers in 23 of 47 chances this season.

    Orioles Stats & Insights

    The Orioles score the 10th-most runs in baseball (224 total, five per game).

    The Baltimore Orioles have hit an MLB-leading 69 home runs, averaging 1.5 per game.

    The Orioles have the 14th-ranked batting average in the majors (.244).

    Baltimore strikes out 8.1 times per game to rank fifth in the majors.

    The pitching staff for the Orioles has a collective 8.6 K/9, which ranks 11th in MLB.

    Baltimore has a 3.32 team ERA that ranks sixth among all MLB pitching staffs.

    Cardinals Stats & Insights

    The Cardinals have scored 181 runs (just 3.9 per game) this season, which ranks 28th in MLB.

    St. Louis ranks 26th in Major League Baseball with just 39 home runs as a team.

    The Cardinals’ .232 batting average ranks 21st in the league this season.

    St. Louis ranks 16th in strikeouts per game (8.7) among MLB offenses.

    The Cardinals have an 8.4 K/9 this season as a pitching staff, which ranks 21st in the big leagues.

    St. Louis pitchers have a combined ERA of 4.42 ERA this year, which ranks 22nd in MLB.

    Orioles Key Players to Watch

    Means gets the start for the Orioles, his fourth of the season. He is 2-0 with a 3.06 ERA and 15 strikeouts in 17 2/3 innings pitched.

    Henderson is batting .271 this season with a team-high 16 home runs and 34 RBI.

    Adley Rutschman leads Baltimore in batting with a .304 average while slugging nine homers and driving in 28 runs.

    Jordan Westburg has collected 47 base hits, an OBP of .345 and a slugging percentage of .519 this season.

    Anthony Santander has collected 33 hits this season and has an OBP of .283. He’s slugging .416 on the year.

    Cardinals Key Players to Watch

    Gibson (3-2) will take to the mound for the Cardinals and make his 10th start of the season.

    Brendan Donovan is hitting .232 with 11 doubles, a triple, four home runs and 17 walks.

    Nolan Arenado’s 22 runs batted in pace his team.

    Lars Nootbaar is hitting .213 with seven doubles, five home runs and 22 walks.

    Masyn Winn is hitting .288 to pace his team.

    Orioles and Cardinals Injuries

    Orioles: Tyler Wells: 15 Day IL (Elbow), Felix Bautista: 60 Day IL (Elbow)

    Cardinals: Willson Contreras: 10 Day IL (Arm), Steven Matz: 15 Day IL (Back), Giovanny Gallegos: 15 Day IL (Shoulder), Keynan Middleton: 15 Day IL (Forearm), Riley O’Brien: 60 Day IL (Forearm), Drew Rom: 60 Day IL (Biceps), Tommy Edman: 60 Day IL (Wrist)

    Orioles vs. Cardinals Prediction

  • Score Prediction: Orioles 5, Cardinals 4
  • Total Prediction: Under 9 runs
  • How to Bet on Orioles vs. Cardinals

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