In a Saturday MLB slate that features 16 exciting matchups, the Arizona Diamondbacks versus the Houston Astros is a game to watch, and we offer best bets for every game here.
MLB picks today
Washington Nationals at Pittsburgh Pirates Odds, Lines & Predictions
Game info
When: 1:35 PM ET
Where: PNC Park
TV Channel: SportsNet PT
Records: Pirates (66-75), Nationals (63-78)
Best bets
Moneyline: Pirates (-125) | Nationals (+105)
Computer Moneyline Pick: Pirates over the Nationals
Total: 8.5
Computer Total Prediction: Under (8.5)
Watch MLB all season long on Fubo
New York Yankees at Chicago Cubs Odds, Lines & Predictions
Game info
When: 2:20 PM ET
Where: Wrigley Field
TV Channel: YES
Records: Cubs (72-70), Yankees (82-60)
Best bets
Moneyline: Yankees (-140) | Cubs (+120)
Computer Moneyline Pick: Cubs over the Yankees
Total: 7.5
Computer Total Prediction: Over (7.5)
Watch MLB all season long on Fubo
Tampa Bay Rays at Baltimore Orioles Odds, Lines & Predictions
Game info
When: 4:05 PM ET
Where: Oriole Park at Camden Yards
TV Channel: MASN
Records: Orioles (82-61), Rays (70-72)
Best bets
Moneyline: Orioles (-185) | Rays (+150)
Computer Moneyline Pick: Orioles over the Rays
Total: 7
Computer Total Prediction: Over (7)
Watch MLB all season long on Fubo
Best Baseball Promo Codes
Detroit Tigers at Oakland Athletics Odds, Lines & Predictions
Game info
When: 4:07 PM ET
Where: Oakland-Alameda County Coliseum
TV Channel: BSDET
Records: Athletics (62-81), Tigers (72-71)
Best bets
Moneyline: Tigers (-115) | Athletics (-105)
Computer Moneyline Pick: Athletics over the Tigers
Total: 8
Computer Total Prediction: Under (8)
Watch MLB all season long on Fubo
Cincinnati Reds at New York Mets Odds, Lines & Predictions
Game info
When: 4:10 PM ET
Where: Citi Field
TV Channel: SNY
Records: Mets (78-64), Reds (68-75)
Best bets
Moneyline: Mets (-155) | Reds (+130)
Computer Moneyline Pick: Mets over the Reds
Total: 8.5
Computer Total Prediction: Under (8.5)
Watch MLB all season long on Fubo
Arizona Diamondbacks at Houston Astros Odds, Lines & Predictions
Game info
When: 4:10 PM ET
Where: Minute Maid Park
TV Channel: ARID
Records: Astros (77-65), Diamondbacks (79-64)
Best bets
Moneyline: Astros (-155) | Diamondbacks (+130)
Computer Moneyline Pick: Astros over the Diamondbacks
Total: 8
Computer Total Prediction: Over (8)
Watch MLB all season long on Fubo
Philadelphia Phillies at Miami Marlins Odds, Lines & Predictions
Game info
When: 4:10 PM ET
Where: LoanDepot park
TV Channel: NBCS-PH
Records: Marlins (53-89), Phillies (85-57)
Best bets
Moneyline: Phillies (-250) | Marlins (+200)
Computer Moneyline Pick: Phillies over the Marlins
Total: 8.5
Computer Total Prediction: Over (8.5)
Watch MLB all season long on Fubo
Washington Nationals at Pittsburgh Pirates Odds, Lines & Predictions
Game info
When: 6:40 PM ET
Where: PNC Park
TV Channel: SportsNet PT
Records: Pirates (66-75), Nationals (63-78)
Best bets
Moneyline: Pirates (-140) | Nationals (+115)
Computer Moneyline Pick: Pirates over the Nationals
Total: 7.5
Computer Total Prediction: Over (7.5)
Watch MLB all season long on Fubo
Los Angeles Angels at Texas Rangers Odds, Lines & Predictions
Game info
When: 7:05 PM ET
Where: Globe Life Field
Records: Rangers (68-74), Angels (59-82)
Best bets
Moneyline: Rangers (-150) | Angels (+125)
Computer Moneyline Pick: Rangers over the Angels
Total: 8.5
Computer Total Prediction: Over (8.5)
Watch MLB all season long on Fubo
Colorado Rockies at Milwaukee Brewers Odds, Lines & Predictions
Game info
When: 7:10 PM ET
Where: American Family Field
TV Channel: COLR
Records: Brewers (81-60), Rockies (53-89)
Best bets
Moneyline: Brewers (-300) | Rockies (+240)
Computer Moneyline Pick: Brewers over the Rockies
Total: 8.5
Computer Total Prediction: Over (8.5)
Watch MLB all season long on Fubo
Chicago White Sox at Boston Red Sox Odds, Lines & Predictions
Game info
When: 7:15 PM ET
Where: Fenway Park
TV Channel: FOX
Records: Red Sox (71-70), White Sox (32-110)
Best bets
Moneyline: Red Sox (-200) | White Sox (+165)
Computer Moneyline Pick: Red Sox over the White Sox
Total: 8.5
Computer Total Prediction: Under (8.5)
Watch MLB all season long on Fubo
Seattle Mariners at St. Louis Cardinals Odds, Lines & Predictions
Game info
When: 7:15 PM ET
Where: Busch Stadium
TV Channel: BSMW
Records: Cardinals (71-70), Mariners (72-70)
Best bets
Moneyline: Mariners (-135) | Cardinals (+115)
Computer Moneyline Pick: Cardinals over the Mariners
Total: 7
Computer Total Prediction: Over (7)
Watch MLB all season long on Fubo
Minnesota Twins at Kansas City Royals Odds, Lines & Predictions
Game info
When: 7:15 PM ET
Where: Kauffman Stadium
TV Channel: FOX
Records: Royals (77-65), Twins (76-65)
Best bets
Moneyline: Twins (-140) | Royals (+120)
Computer Moneyline Pick: Royals over the Twins
Total: 8
Computer Total Prediction: Over (8)
Watch MLB all season long on Fubo
Toronto Blue Jays at Atlanta Braves Odds, Lines & Predictions
Game info
When: 7:20 PM ET
Where: Truist Park
TV Channel: BSSE
Records: Braves (77-64), Blue Jays (67-75)
Best bets
Moneyline: Braves (-160) | Blue Jays (+135)
Computer Moneyline Pick: Braves over the Blue Jays
Total: 7.5
Computer Total Prediction: Over (7.5)
Watch MLB all season long on Fubo
San Francisco Giants at San Diego Padres Odds, Lines & Predictions
Game info
When: 8:40 PM ET
Where: PETCO Park
TV Channel: NBCS-BA
Records: Padres (81-62), Giants (69-73)
Best bets
Moneyline: Padres (-135) | Giants (+110)
Computer Moneyline Pick: Padres over the Giants
Total: 7
Computer Total Prediction: Over (7)
Watch MLB all season long on Fubo
Cleveland Guardians at Los Angeles Dodgers Odds, Lines & Predictions
Game info
When: 9:10 PM ET
Where: Dodger Stadium
TV Channel: BSGL
Records: Dodgers (84-57), Guardians (81-60)
Best bets
Moneyline: Dodgers (-155) | Guardians (+125)
Computer Moneyline Pick: Dodgers over the Guardians
Total: 9
Computer Total Prediction: Under (9)
Watch MLB all season long on Fubo
How to Bet on Baseball
Get more MLB picks.
If you are new to sports betting, read our in-depth guide on betting on Baseball and find the best MLB betting sites and promo codes.