In a Wednesday MLB slate that has 14 competitive matchups, the San Diego Padres versus the Los Angeles Dodgers is a game to catch, and we have best bets for each game in this article.
MLB picks today
Seattle Mariners at Houston Astros Odds, Lines & Predictions
Game info
When: 2:10 PM ET
Where: Minute Maid Park
TV Channel: SCHN
Records: Astros (86-73), Mariners (82-77)
Best bets
Moneyline: Mariners (-155) | Astros (+130)
Computer Moneyline Pick: Astros over the Mariners
Total: 7
Computer Total Prediction: Over (7)
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Chicago Cubs at Philadelphia Phillies Odds, Lines & Predictions
Game info
When: 6:05 PM ET
Where: Citizens Bank Park
TV Channel: MARQ
Records: Phillies (93-65), Cubs (81-77)
Best bets
Moneyline: Phillies (-210) | Cubs (+170)
Computer Moneyline Pick: Phillies over the Cubs
Total: 8
Computer Total Prediction: Over (8)
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Cincinnati Reds at Cleveland Guardians Odds, Lines & Predictions
Game info
When: 6:40 PM ET
Where: Progressive Field
TV Channel: BSGL
Records: Guardians (91-67), Reds (76-82)
Best bets
Moneyline: Guardians (-150) | Reds (+125)
Computer Moneyline Pick: Guardians over the Reds
Total: 8
Computer Total Prediction: Over (8)
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Milwaukee Brewers at Pittsburgh Pirates Odds, Lines & Predictions
Game info
When: 6:40 PM ET
Where: PNC Park
TV Channel: SportsNet PT
Records: Pirates (73-84), Brewers (90-67)
Best bets
Moneyline: Brewers (-155) | Pirates (+130)
Computer Moneyline Pick: Brewers over the Pirates
Total: 7.5
Computer Total Prediction: Over (7.5)
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Tampa Bay Rays at Detroit Tigers Odds, Lines & Predictions
Game info
When: 6:40 PM ET
Where: Comerica Park
TV Channel: BSDET
Records: Tigers (83-74), Rays (78-79)
Best bets
Moneyline: Tigers (-130) | Rays (+110)
Computer Moneyline Pick: Tigers over the Rays
Total: 8
Computer Total Prediction: Over (8)
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Kansas City Royals at Washington Nationals Odds, Lines & Predictions
Game info
When: 6:45 PM ET
Where: Nationals Park
TV Channel: MASN2
Records: Nationals (69-88), Royals (83-74)
Best bets
Moneyline: Royals (-140) | Nationals (+120)
Computer Moneyline Pick: Royals over the Nationals
Total: 7.5
Computer Total Prediction: Over (7.5)
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Baltimore Orioles at New York Yankees Odds, Lines & Predictions
Game info
When: 7:05 PM ET
Where: Yankee Stadium
TV Channel: YES
Records: Yankees (92-65), Orioles (87-70)
Best bets
Moneyline: Yankees (-130) | Orioles (+110)
Computer Moneyline Pick: Yankees over the Orioles
Total: 8.5
Computer Total Prediction: Over (8.5)
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Boston Red Sox at Toronto Blue Jays Odds, Lines & Predictions
Game info
When: 7:07 PM ET
Where: Rogers Centre
TV Channel: NESN
Records: Blue Jays (73-85), Red Sox (80-78)
Best bets
Moneyline: Blue Jays (-130) | Red Sox (+110)
Computer Moneyline Pick: Blue Jays over the Red Sox
Total: 7.5
Computer Total Prediction: Over (7.5)
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Miami Marlins at Minnesota Twins Odds, Lines & Predictions
Game info
When: 7:40 PM ET
Where: Target Field
TV Channel: BSFL
Records: Twins (81-76), Marlins (58-99)
Best bets
Moneyline: Twins (-190) | Marlins (+155)
Computer Moneyline Pick: Twins over the Marlins
Total: 8.5
Computer Total Prediction: Over (8.5)
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Los Angeles Angels at Chicago White Sox Odds, Lines & Predictions
Game info
When: 7:40 PM ET
Where: Guaranteed Rate Field
TV Channel: BSW
Records: White Sox (37-120), Angels (63-94)
Best bets
Moneyline: Angels (-120) | White Sox (+100)
Computer Moneyline Pick: Angels over the White Sox
Total: 7.5
Computer Total Prediction: Over (7.5)
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St. Louis Cardinals at Colorado Rockies Odds, Lines & Predictions
Game info
When: 8:40 PM ET
Where: Coors Field
TV Channel: BSMW
Records: Rockies (60-97), Cardinals (80-77)
Best bets
Moneyline: Cardinals (-130) | Rockies (+110)
Computer Moneyline Pick: Cardinals over the Rockies
Total: 10.5
Computer Total Prediction: Under (10.5)
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Texas Rangers at Oakland Athletics Odds, Lines & Predictions
Game info
When: 9:40 PM ET
Where: Oakland-Alameda County Coliseum
TV Channel: BSSW
Records: Athletics (68-89), Rangers (74-83)
Best bets
Moneyline: Athletics (-115) | Rangers (-105)
Computer Moneyline Pick: Athletics over the Rangers
Total: 7.5
Computer Total Prediction: Under (7.5)
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San Francisco Giants at Arizona Diamondbacks Odds, Lines & Predictions
Game info
When: 9:40 PM ET
Where: Chase Field
TV Channel: ARID
Records: Diamondbacks (87-71), Giants (79-79)
Best bets
Moneyline: Diamondbacks (-250) | Giants (+190)
Computer Moneyline Pick: Diamondbacks over the Giants
Total: 8.5
Computer Total Prediction: Over (8.5)
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San Diego Padres at Los Angeles Dodgers Odds, Lines & Predictions
Game info
When: 10:10 PM ET
Where: Dodger Stadium
TV Channel: SDPA
Records: Dodgers (93-64), Padres (91-66)
Best bets
Moneyline: Dodgers (-130) | Padres (+110)
Computer Moneyline Pick: Dodgers over the Padres
Total: 8
Computer Total Prediction: Over (8)
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