Giants vs. Guardians Prediction: Expert Picks, Odds, Stats & Best Bets – Wednesday, September 13, 2023

The San Francisco Giants (74-71) are -143 favorites to take Game 3 of th series from the Cleveland Guardians (69-77) Wednesday at 3:45 PM ET. The teams enter the matchup with the series record tied, and the underdog Guardians are listed with +121 odds to win the rubber match and take the series victory.

Kyle Harrison starts for San Francisco while Logan Allen is Cleveland’s starter for the contest.

Giants vs. Guardians Odds

  • Giants odds to win: -143
  • Guardians odds to win: +121
  • Spread: Giants -1.5
  • Total: 7.5 runs
  • Giants vs. Guardians Promo Codes

    Who Will Win Giants vs. Guardians?

    Giants and Guardians Betting Trends

    The Giants have compiled a 41-33 record in games they were favored on the moneyline (winning 55.4% of those games).

    San Francisco has a record of 20-18 when it has played as moneyline favorites with odds of -143 or shorter (52.6% winning percentage).

    The Guardians have entered the game as underdogs 75 times this season and won 33, or 44%, of those games.

    Cleveland has a record of 11-21 in games where oddsmakers have it as underdogs of at least +121 on the moneyline.

    The Giants have combined with opponents to go over the total 62 times this season for a 62-79-3 record against the over/under.

    Games involving the Guardians have gone over the total set by bookmakers in 60 of 144 chances this season.

    Giants Stats & Insights

    The Giants are the 22nd-highest scoring team in MLB action averaging 4.3 runs per game (624 total).

    San Francisco averages 1.1 home runs per game to rank 19th in MLB action with 159 total home runs .

    The Giants are 22nd in MLB with a .240 batting average.

    San Francisco strikes out 9.3 times per game to rank 25th in MLB.

    The pitching staff for the Giants has a collective 8.6 K/9, which ranks 17th in MLB.

    San Francisco has the 11th-ranked team ERA across all MLB pitching staffs (4.03).

    Guardians Stats & Insights

    The Guardians are among the lowest scoring teams in the league, ranking 28th with just 586 total runs (four per game) this season.

    Cleveland’s 110 home runs rank last in MLB this season.

    The Guardians rank 17th in MLB with a .247 team batting average.

    Cleveland has shown good bat-to-ball skills at the plate this season with the second-best strikeout rate (7.1 per game) among MLB offenses.

    The Guardians strike out just 8.1 batters per nine innings as a pitching staff, which ranks 26th in MLB.

    Cleveland pitchers have a combined ERA of 3.96 ERA this year, sixth-best in baseball.

    Giants Key Players to Watch

    Harrison (1-1 with a 4.87 ERA and 26 strikeouts in 20 1/3 innings pitched) makes the start for the Giants, his fifth of the season.

    Wilmer Flores leads San Francisco in home runs this season with 22 while driving in 54 runs.

    LaMonte Wade Jr has collected 101 hits this season and has an OBP of .373. He’s slugging .406 on the year.

    Thairo Estrada leads San Francisco with a .270 batting average while slugging 12 homers and driving in 45 runs.

    J.D. Davis leads San Francisco in runs batted in with 65 while batting .251 with 17 homers.

    Guardians Key Players to Watch

    The Guardians’ Allen (7-7) will make his 23rd start of the season.

    Jose Ramirez leads the Guardians with 22 home runs and has put up a team-best batting average of .275.

    Steven Kwan is hitting .270 with 32 doubles, six triples, five home runs and 60 walks.

    Josh Naylor paces the Guardians with 87 runs batted in.

    Andres Gimenez has 25 doubles, four triples, 12 home runs and 32 walks while batting .240.

    Giants and Guardians Injuries

    Giants: Michael Conforto: 10 Day IL (Hamstring), Ross Stripling: 15 Day IL (Back), Anthony DeSclafani: 60 Day IL (Elbow), Mark Mathias: 60 Day IL (Shoulder), Cole Waites: 60 Day IL (Elbow), Roberto PĂ©rez: 60 Day IL (Shoulder), Thomas Szapucki: 60 Day IL (Arm)

    Guardians: Michael Kelly: 15 Day IL (Back), Shane Bieber: 60 Day IL (Elbow), Triston McKenzie: 60 Day IL (Elbow)

    Giants vs. Guardians Prediction

  • Score Prediction: Giants 5, Guardians 4
  • Total Prediction: Over 7.5 runs
  • How to Bet on Giants vs. Guardians

    Get more MLB picks.
    If you are new to sports betting, read our in-depth guide on betting on Baseball and find the best MLB betting sites and promo codes.

    written by

    Matt is from the Chicagoland area and has been working in Chicago sports since 2015 with stops at WGN Radio, the Chicago Blackhawks, Stadium, and NBC Sports Chicago prior to landing at Betsperts. Matt covers just about everything for Betsperts and Bleacher Nation but focuses on the NHL and college football.

    more mlb-picks news

    Diamondbacks vs. Rangers Probable Starting Pitchers – World Series Game 5

    The Texas Rangers (90-72) play on Wednesday in Phoenix against the Arizona Diamondbacks (84-78). First pitch is at 8:03 PM ET.The probable pitchers are Zac Gallen (17-9, 3.47 ERA) for the Diamondbacks and Nathan Eovaldi (12-5, 3.63 ERA) for the...

    Diamondbacks vs. Rangers Prediction: Expert Picks, Odds, Stats & Best Bets – World Series Game 5

    The Arizona Diamondbacks (84-78) host the Texas Rangers (90-72) on Wednesday at 8:03 PM ET(broadcast on FOX). Sportsbooks have opted not to choose a favorite on the moneyline for the contest, installing pick 'em odds, instead. Bookmakers have not named...

    Diamondbacks vs. Rangers Prediction: Expert Picks, Odds, Stats & Best Bets – World Series Game 4

    Game 4 of the World Series will feature the Arizona Diamondbacks playing host to the Texas Rangers. The Rangers will hope to extend their series lead and move closer to winning it all when action gets underway on Tuesday starting...

    Diamondbacks vs. Rangers Probable Starting Pitchers – World Series Game 4

    The Texas Rangers (90-72) visit the Arizona Diamondbacks (84-78) for a road game on Tuesday at 8:03 PM ET.The Diamondbacks will call on Joe Mantiply (2-2, 4.62 ERA) versus the Rangers and Andrew Heaney (10-6, 4.15 ERA).Diamondbacks vs. Rangers Pitcher...

    Rangers vs. Diamondbacks Prediction: Expert Picks, Odds, Stats & Best Bets – World Series Game 3

    The Texas Rangers will visit the Arizona Diamondbacks in the third game of the World Series on Monday at 8:03 PM ET, live on FOX from Chase Field. The teams split the first two games and will look to break...

    Rangers vs. Diamondbacks Prediction: Expert Picks, Odds, Stats & Best Bets – World Series Game 3

    The Texas Rangers will visit the Arizona Diamondbacks in the third game of the World Series on Monday at 8:03 PM ET, live on FOX from Chase Field. The teams split the first two games and will look to break...

    Rangers vs. Diamondbacks Probable Starting Pitchers – World Series Game 3

    The Arizona Diamondbacks (84-78) play at home against the Texas Rangers (90-72) at Chase Field. The matchup is set to begin at 8:03 PM ET on Monday.The probable starters are Max Scherzer (13-6, 3.77 ERA) for the Rangers and Brandon...

    Rangers vs. Diamondbacks Prediction: Expert Picks, Odds, Stats & Best Bets – World Series Game 3

    Game 3 of the World Series on Monday will feature the Texas Rangers traveling to take on the Arizona Diamondbacks. The teams will look to break the 1-1 series deadlock when action begins at 8:03 PM ET on FOX, live...

    Rangers vs. Diamondbacks Prediction: Expert Picks, Odds, Stats & Best Bets – World Series Game 2

    The Texas Rangers will host the Arizona Diamondbacks in the second game of the World Series on Saturday at 8:03 PM ET, live on FOX from Globe Life Field. The Diamondbacks will look to bounce back after falling behind in...

    Rangers vs. Diamondbacks Probable Starting Pitchers – World Series Game 2

    Following a stretch of three consecutive wins, the Texas Rangers (90-72) face the Arizona Diamondbacks (84-78) at 8:03 PM ET on Saturday.The Rangers will call on Jordan Montgomery (10-11, 3.20 ERA) against the Diamondbacks and Merrill Kelly (12-8, 3.29 ERA).Rangers...

    Latest News

    Noah Fant Fantasy Week 14: Projections vs. 49ers, Points and Stats, Start or Sit

    Tight end Noah Fant faces a matchup versus the 14th-ranked pass defense in the NFL (219.4 yards allowed per game) in Week 14, when his Seattle Seahawks play the San Francisco 49ers, Sunday at 4:05 PM ET.Is Fant's game against...

    Isaiah Hodgins Fantasy Week 14: Projections vs. Packers, Points and Stats, Start or Sit

    Wideout Isaiah Hodgins has a matchup against the 10th-ranked pass defense in the league (203.8 yards allowed per game) in Week 14, when his New York Giants take on the Green Bay Packers, Monday at 8:15 PM ET.With his upcoming...

    Names Are Being Discussed in Tyler Glasnow Trade Talks, But Cubs Aren’t Alone

    Tyler Glasnow made a ton of sense as an addition for the Cubs in conjunction with Shohei Ohtani in part because of the whole Ohtani-can't-pitch-in-2024 thing, in tandem with the Glasnow-is-under-contract-for-only-2024 thing. Fun to think about the combo. But even...

    Trae Young Player Props: Three-Pointer Props and Odds vs. the Nets – Wednesday, December 6, 2023

    The Atlanta Hawks play the Brooklyn Nets at 7:30 PM ET on Wednesday, and one of the 3-pointer props available for this matchup requires four trifectas from Trae Young.Trae Young's Three-Pointer Prop Odds vs. the NetsTrae Young's over/under for three-pointers...

    Zach Collins Player Props: Three-Pointer Props and Odds vs. the Timberwolves – Wednesday, December 6, 2023

    The San Antonio Spurs meet the Minnesota Timberwolves at 7:30 PM ET on Wednesday, and one of the 3-pointer over/unders available for this clash requires two treys from Zach Collins.Zach Collins' Three-Pointer Prop Odds vs. the TimberwolvesZach Collins' over/under for...

    Max Strus Player Props: Three-Pointer Props and Odds vs. the Magic – Wednesday, December 6, 2023

    On Wednesday at 7:00 PM ET, the Cleveland Cavaliers play the Orlando Magic, and Max Strus' 3-pointer over/under for this matchup requires three treys.Max Strus' Three-Pointer Prop Odds vs. the MagicMax Strus' over/under for three-pointers in this game: 2.5 at...

    Desmond Bane Player Props: Three-Pointer Props and Odds vs. the Pistons – Wednesday, December 6, 2023

    Desmond Bane's Memphis Grizzlies play the Detroit Pistons on Wednesday at 7:00 PM ET, and to beat his 3-point prop, he must make four from beyond the arc.Desmond Bane's Three-Pointer Prop Odds vs. the PistonsDesmond Bane's over/under for three-pointers in...

    Keldon Johnson Player Props: Three-Pointer Props and Odds vs. the Timberwolves – Wednesday, December 6, 2023

    At 7:30 PM ET on Wednesday, it'll be the San Antonio Spurs versus the Minnesota Timberwolves, with Keldon Johnson needing two treys to beat his 3-pointer prop.Keldon Johnson's Three-Pointer Prop Odds vs. the TimberwolvesKeldon Johnson's over/under for three-pointers in this...

    Victor Wembanyama Player Props: Three-Pointer Props and Odds vs. the Timberwolves – Wednesday, December 6, 2023

    Victor Wembanyama's San Antonio Spurs play the Minnesota Timberwolves on Wednesday at 7:30 PM ET, and to beat his 3-point over/under, he must make two from beyond the arc.Victor Wembanyama's Three-Pointer Prop Odds vs. the TimberwolvesVictor Wembanyama's over/under for three-pointers...

    Joel Embiid Player Props: Three-Pointer Props and Odds vs. the Wizards – Wednesday, December 6, 2023

    Joel Embiid's Philadelphia 76ers meet the Washington Wizards on Wednesday at 7:00 PM ET, and to beat his 3-point over/under, he must make two from beyond the arc.Joel Embiid's Three-Pointer Prop Odds vs. the WizardsJoel Embiid's over/under for three-pointers in...

    more mlb-picks news

    Latest News