Giants vs. Guardians Prediction: Expert Picks, Odds, Stats & Best Bets – Wednesday, September 13, 2023

The San Francisco Giants (74-71) are -143 favorites to take Game 3 of th series from the Cleveland Guardians (69-77) Wednesday at 3:45 PM ET. The teams enter the matchup with the series record tied, and the underdog Guardians are listed with +121 odds to win the rubber match and take the series victory.

Kyle Harrison starts for San Francisco while Logan Allen is Cleveland’s starter for the contest.

Giants vs. Guardians Odds

  • Giants odds to win: -143
  • Guardians odds to win: +121
  • Spread: Giants -1.5
  • Total: 7.5 runs
  • Giants vs. Guardians Promo Codes

    Who Will Win Giants vs. Guardians?

    Giants and Guardians Betting Trends

    The Giants have compiled a 41-33 record in games they were favored on the moneyline (winning 55.4% of those games).

    San Francisco has a record of 20-18 when it has played as moneyline favorites with odds of -143 or shorter (52.6% winning percentage).

    The Guardians have entered the game as underdogs 75 times this season and won 33, or 44%, of those games.

    Cleveland has a record of 11-21 in games where oddsmakers have it as underdogs of at least +121 on the moneyline.

    The Giants have combined with opponents to go over the total 62 times this season for a 62-79-3 record against the over/under.

    Games involving the Guardians have gone over the total set by bookmakers in 60 of 144 chances this season.

    Giants Stats & Insights

    The Giants are the 22nd-highest scoring team in MLB action averaging 4.3 runs per game (624 total).

    San Francisco averages 1.1 home runs per game to rank 19th in MLB action with 159 total home runs .

    The Giants are 22nd in MLB with a .240 batting average.

    San Francisco strikes out 9.3 times per game to rank 25th in MLB.

    The pitching staff for the Giants has a collective 8.6 K/9, which ranks 17th in MLB.

    San Francisco has the 11th-ranked team ERA across all MLB pitching staffs (4.03).

    Guardians Stats & Insights

    The Guardians are among the lowest scoring teams in the league, ranking 28th with just 586 total runs (four per game) this season.

    Cleveland’s 110 home runs rank last in MLB this season.

    The Guardians rank 17th in MLB with a .247 team batting average.

    Cleveland has shown good bat-to-ball skills at the plate this season with the second-best strikeout rate (7.1 per game) among MLB offenses.

    The Guardians strike out just 8.1 batters per nine innings as a pitching staff, which ranks 26th in MLB.

    Cleveland pitchers have a combined ERA of 3.96 ERA this year, sixth-best in baseball.

    Giants Key Players to Watch

    Harrison (1-1 with a 4.87 ERA and 26 strikeouts in 20 1/3 innings pitched) makes the start for the Giants, his fifth of the season.

    Wilmer Flores leads San Francisco in home runs this season with 22 while driving in 54 runs.

    LaMonte Wade Jr has collected 101 hits this season and has an OBP of .373. He’s slugging .406 on the year.

    Thairo Estrada leads San Francisco with a .270 batting average while slugging 12 homers and driving in 45 runs.

    J.D. Davis leads San Francisco in runs batted in with 65 while batting .251 with 17 homers.

    Guardians Key Players to Watch

    The Guardians’ Allen (7-7) will make his 23rd start of the season.

    Jose Ramirez leads the Guardians with 22 home runs and has put up a team-best batting average of .275.

    Steven Kwan is hitting .270 with 32 doubles, six triples, five home runs and 60 walks.

    Josh Naylor paces the Guardians with 87 runs batted in.

    Andres Gimenez has 25 doubles, four triples, 12 home runs and 32 walks while batting .240.

    Giants and Guardians Injuries

    Giants: Michael Conforto: 10 Day IL (Hamstring), Ross Stripling: 15 Day IL (Back), Anthony DeSclafani: 60 Day IL (Elbow), Mark Mathias: 60 Day IL (Shoulder), Cole Waites: 60 Day IL (Elbow), Roberto Pérez: 60 Day IL (Shoulder), Thomas Szapucki: 60 Day IL (Arm)

    Guardians: Michael Kelly: 15 Day IL (Back), Shane Bieber: 60 Day IL (Elbow), Triston McKenzie: 60 Day IL (Elbow)

    Giants vs. Guardians Prediction

  • Score Prediction: Giants 5, Guardians 4
  • Total Prediction: Over 7.5 runs
  • How to Bet on Giants vs. Guardians

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    written by

    Matt is from the Chicagoland area and has been working in Chicago sports since 2015 with stops at WGN Radio, the Chicago Blackhawks, Stadium, and NBC Sports Chicago prior to landing at Betsperts. Matt covers just about everything for Betsperts and Bleacher Nation but focuses on the NHL and college football.

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